Either increases toxicity of the other by Other (see comment). Consult your doctor for more details and to discuss the use of reliable forms of birth control while taking this medication. Avoid or Use Alternate Drug. Monitor Closely (1)perindopril, amiloride. Use Caution/Monitor. Additive hypotensive effects. Avoid or Use Alternate Drug.verapamil increases levels of bosutinib by P-glycoprotein (MDR1) efflux transporter. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. verapamil, nadolol. Use Caution/Monitor. Contraindicated. Increased risk of orthostatic hypotension. Avoid or Use Alternate Drug. Effect of interaction is not clear, use caution. Use Caution/Monitor. Either increases toxicity of the other by Mechanism: pharmacodynamic synergism. Enhanced antiplatelet activity. Many manufacturers source their beta-glucan from substances like baker's yeast. Coadministration with drugs that reduce renal function or compete for active tubular secretion may increase serum concentrations of either entecavir or the coadministered drug. The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1; coadministration with OATP1B1 inhibitors may increase valsartan systemic exposure. Use Caution/Monitor. Avoid or Use Alternate Drug. Use Caution/Monitor.nabumetone decreases effects of valsartan by pharmacodynamic antagonism. Use Caution/Monitor. . 2.5-5 mg IV over 2 minutes; 5-10 mg dose may be repeated after 15-30 minutes, Alternatively, 0.075-0.15 mg/kg (not to exceed 10 mg) IV over 2 minutes; dose may be repeated once 30 minutes after first dose, Treatment of chronic atrial fibrillation (rate control); prevention of paroxysmal supraventricular tachycardia, Immediate release: 240-480 mg/day PO divided q6-8hr, 40 mg PO q8hr; may be titrated to 120 mg q8hr, Renal impairment: Use with caution; monitor ECG; for Verelan PM, manufacturer recommends 100 mg at bedtime initially; if CrCl <10 mL/min, reduce dose by 25-50%, Hepatic impairment: In cirrhosis, reduce dose by 20-50% of normal for oral and IV administration, 1-15 years old: 0.1-0.3 mg/kg (not to exceed 5 mg) IV over 2 minutes; second dose (not to exceed 10 mg) may be given after 30 minutes, Alternatively (not well established), 4-8 mg/kg/day PO divided q8hr, In general, lower initial doses are warranted; doses should be adjusted on basis of clinical response, Immediate release: 80 mg PO q8hr initially; usual range: 80-120 mg PO q8hr; not to exceed 480 mg/day, Extended release (Covera-HS): 180 mg PO at bedtime initially; maintenance: 180-540 mg PO at bedtime, Immediate release: 40 mg PO q8hr initially; maintenance: 80-320 mg PO q12hr, Extended release (Calan SR, Isoptin SR, Verelan): 120 mg/day PO given in morning, Extended release (Covera-HS): 180 mg/day PO at bedtime, Extended release (Verelan PM): 100 mg/day PO at bedtime. NSAIDs decrease prostaglandin synthesis. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. Increases lomitapide levels several folds.Monitor Closely (1)lomitapide increases levels of verapamil by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. WebDosage. Monitor Closely (1)verapamil will increase the level or effect of dienogest/estradiol valerate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. hydralazine, procarbazine. Use Caution/Monitor. Monitor Closely (2)valsartan increases effects of insulin inhaled by unspecified interaction mechanism. ketorolac decreases effects of valsartan by pharmacodynamic antagonism. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)verapamil will increase the level or effect of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Serious - Use Alternative (1)verapamil will increase the level or effect of edoxaban by P-glycoprotein (MDR1) efflux transporter. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. ACE inhibitor induced Na+ depletion may increase reabsorption of lithium from renal tubule. Use Caution/Monitor. Coadministration of flibanserin with moderate or strong CYP3A4 inhibitors is contraindicated. sacubitril/valsartan, perindopril. Comment: Verapamil levels may incr or decr, due to contradictory effects of tipranavir on hepatic CYP3A4 and P glycoprotein.tipranavir will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil will increase the level or effect of atazanavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Possible additive effect of magnesium and calcium channel blockers on reduction of ionic calcium may increase risk of hypotension or muscle weakness. Avoid or Use Alternate Drug. verapamil will increase the level or effect of amitriptyline by P-glycoprotein (MDR1) efflux transporter. Risk of hyperkalemia. Use Caution/Monitor. Use Caution/Monitor.verapamil will increase the level or effect of conjugated estrogens, vaginal by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. PRECAUTIONS: Before taking perindopril, tell your doctor or pharmacist if you are allergic to it; or to other ACE inhibitors (such as captopril, lisinopril); or if you have any other allergies. The typical dosage range for this product as an oral dietary supplement is between 300-1800 mg daily, split into 1-3 dosages per day. According to a 2011 report, the beta-glucan found in oats may help keep cholesterol in check. Use Caution/Monitor. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Either increases effects of the other by pharmacodynamic synergism. You can support a healthy immune system by getting enough sleep, exercising, eating a healthy diet, and generally taking care of yourself. After discontinuation of the strong or moderate CYP3A4 inhibitor for 3 elimination half-lives, resume selumetinib dose that was taken before initiating the inhibitor. Monitor Closely (1)rucaparib will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Modify Therapy/Monitor Closely. Either increases effects of the other by pharmacodynamic synergism. hydralazine, isoproterenol. Use Caution/Monitor. Use Caution/Monitor. Minor/Significance Unknown. Coadministration of encorafenib with sensitive CYP3A4 substrates may result in increased toxicity or decreased efficacy of these agents. Use Caution/Monitor. Decrease suvorexant starting dose to 5 mg HS if coadministered with moderate CYP3A4 inhibitors. Risk of fetal compromise if given during pregnancy. Use Caution/Monitor.penbutolol, valsartan. Use Caution/Monitor. Enhanced antiplatelet activity. perindopril, etodolac. Monitor Closely (1)verapamil will increase the level or effect of lumateperone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. pharmacodynamic antagonism. verapamil will increase the level or effect of tadalafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)nadolol and verapamil both increase anti-hypertensive channel blocking. Minor/Significance Unknown. Use Caution/Monitor. 80 mg PO q8hr initially; usual range: 80-120 mg PO q8hr; not to exceed 480 mg/day, Covera-HS: 180 mg/day PO at bedtime initially; maintenance: 180-540 mg/day PO at bedtime, 80 mg PO q8hr initially; maintenance: 80-320 mg PO q12hr, Calan, Isoptin SR: 180 mg/day PO given in morning (120 mg/day initially if patient elderly or of small stature); for desired response, may be increased to 240 mg/day, then to 360 mg/day (either 180 mg q12hr or 240 mg in morning and 120 mg in evening), Verelan: 180 mg/day PO (120 mg/day initially if patient elderly or of small stature); for desired response, may be increased to 240 mg/day PO, then by 120 mg/day at weekly intervals; not to exceed 480 mg/day, Verelan PM: 200 mg/day PO at bedtime (100 mg/day if patient elderly or of small stature); may be increased by 100 mg/day at weekly intervals as needed; not to exceed 400 mg/day, Covera-HS: 180 mg/day PO at bedtime (120 mg/day initially if patient elderly or of small stature); for desired response, may be increased to 240 mg/day, then by 120 mg/day at weekly intervals; not to exceed 480 mg/day, elvitegravir/cobicistat/emtricitabine/tenofovir DF, ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC), sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, triamcinolone acetonide injectable suspension. Use Caution/Monitor. Coadministration with moderate and strong CYP3A inhibitors results in increased systemic exposure to amlodipine and may require dose reduction. Risk of fetal compromise if given during pregnancy. valsartan and nabumetone both increase serum potassium. Minor/Significance Unknown. Monitor Closely (2)verapamil will increase the level or effect of imipramine by affecting hepatic enzyme CYP1A2 metabolism. Use Caution/Monitor. Monitor Closely (1)potassium iodide and perindopril both increase serum potassium. Mechanism: pharmacodynamic synergism. Enhanced antiplatelet activity. Use Caution/Monitor. Maitake mushroom has anti-tumor effects (animal/in vitro research). Use Caution/Monitor. Contraindicated. Use Caution/Monitor. Monitor Closely (1)valsartan increases and chlorothiazide decreases serum potassium. Monitor Closely (2)verapamil will increase the level or effect of tacrolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. pharmacodynamic antagonism. fo-ti increases effects of verapamil by pharmacodynamic synergism. Minor/Significance Unknown. Modify Therapy/Monitor Closely. NSAIDs decrease prostaglandin synthesis. cortisone will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor/Significance Unknown. valsartan and tolfenamic acid both increase serum potassium. sulfamethoxazole will increase the level or effect of verapamil by basic (cationic) drug competition for renal tubular clearance. Coadministration may result in a significant decrease in renal function. fluphenazine increases effects of perindopril by unspecified interaction mechanism. Based on available research, the U.S. Food and Drug Administration and the European Food Safety Authority have concluded that consuming three grams of beta glucans per day can help reduce cholesterol levels by about 5 NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor.vemurafenib increases levels of verapamil by P-glycoprotein (MDR1) efflux transporter. Serious - Use Alternative (1)valsartan, quinapril. Minor/Significance Unknown.verapamil increases levels of amitriptyline by decreasing metabolism. Minor/Significance Unknown. crizotinib increases levels of verapamil by P-glycoprotein (MDR1) efflux transporter. Monitor glycemic control especially during the first month of treatment with an ACE inhibitor. St John's Wort will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil will increase the level or effect of daridorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil will increase the level or effect of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil will increase the level or effect of colchicine by Other (see comment). Monitor Closely (1)erythromycin base will increase the level or effect of valsartan by Other (see comment). When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. Monitor Closely (2)verapamil will increase the level or effect of clozapine by affecting hepatic enzyme CYP1A2 metabolism. Modify Therapy/Monitor Closely. Hypersensitivity to hydralazine. verapamil will increase the level or effect of imipramine by affecting hepatic enzyme CYP1A2 metabolism. Minor (1)reishi increases effects of valsartan by pharmacodynamic synergism. Avoid or Use Alternate Drug. Either increases effects of the other by pharmacodynamic synergism. valsartan increases effects of insulin glargine by unspecified interaction mechanism. Monitor Closely (1)xipamide increases effects of hydralazine by pharmacodynamic synergism. verapamil increases levels of bosutinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. This information does not assure that this product is safe, effective, or appropriate for you. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. verapamil will increase the level or effect of deflazacort by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Risk of hypotension. Avoid or Use Alternate Drug. After discontinuing the inhibitor for 3-5 elimination half-lives, resume previous encorafenib dose. Use Caution/Monitor. verapamil will increase the level or effect of mifepristone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. I am excited to add the benefits of mushrooms to my health routine. WARNING: Perindopril can cause serious (possibly fatal) harm to an unborn baby if used during pregnancy. Use Caution/Monitor. Do not exceed simvastatin 10 mg daily when given concurrently. Avoid or substitute another drug for these medications when possible. valsartan increases and hydrochlorothiazide decreases serum potassium. Minor/Significance Unknown. Doses of about 6 grams daily for four weeks had a statistically significant lowering effect on LDL cholesterol levels. Risk of hypotension. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine. With a legacy that spans millennia, Reishi has earned its reputation as mushroom of immortality. Host Defense Reishi is a daily supplement that uses activated, freeze-dried, Certified Organic mycelium with a full spectrum of constituents: polysaccharides (beta glucans, arabinoxylane, glucose, xylose, galactose and mannose), Avoid or Use Alternate Drug. Minor/Significance Unknown. Either increases toxicity of the other by Other (see comment). See zanubrutinib Dosage Modifications for precise recommendation. Coadministration with drugs that reduce renal function or compete for active tubular secretion may increase serum concentrations of either entecavir or the coadministered drug. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor.glecaprevir/pibrentasvir will increase the level or effect of verapamil by P-glycoprotein (MDR1) efflux transporter. Consider decreasing dosage of antihypertensive agent. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Either increases effects of the other by pharmacodynamic synergism. ibuprofen, perindopril. Monitor Closely (1)ketorolac intranasal decreases effects of hydralazine by pharmacodynamic antagonism. Take your next dose at the regular time. If a moderate CYP3A inhibitor must be used, reduce the venetoclax dose by at least 50%. Monitor Closely (1)phenytoin will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep all medical and lab appointments.Check your blood pressure regularly while taking this medication. Monitor Closely (1)aspirin decreases effects of hydralazine by pharmacodynamic antagonism. xipamide increases effects of valsartan by pharmacodynamic synergism. Minor/Significance Unknown. Beta-glucan may prevent cholesterol absorption from food, helping to lower blood cholesterol levels. Monitor Closely (1)valsartan increases effects of insulin regular human by unspecified interaction mechanism. Modify Therapy/Monitor Closely. Use Caution/Monitor. Doses used in studies range from 2 to 6 grams taken orally daily for up to 12 weeks for oat beta-glucan. Minor/Significance Unknown. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Reduce afatinib daily dose by 10 mg if not tolerated when coadministered with P-gp inhibitors. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals.Serious - Use Alternative (1)ibuprofen, perindopril. Use Caution/Monitor. If used together, use lower doses of lovastatin and monitor for lovastatin toxicity (myositis, rhabdomyolysis).Serious - Use Alternative (1)verapamil will increase the level or effect of lovastatin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. To view formulary information first create a list of plans. Use Caution/Monitor. Risk of fetal compromise if given during pregnancy. Monitor Closely (1)hydralazine increases levels of lomitapide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Talk to your doctor if you are using marijuana (cannabis).This medication may increase your potassium levels. Use Caution/Monitor. Reviewed in the United States on September 30, 2022. Use Caution/Monitor. Additive hypotensive effects. Contact the applicable plan diflunisal, perindopril. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and to check in about any potential interactions with other supplements or medications. Avoid or Use Alternate Drug. Use Caution/Monitor.nafcillin decreases levels of verapamil by increasing metabolism. Use Caution/Monitor. Minor/Significance Unknown. verapamil, timolol. Serious - Use Alternative (2)verapamil will increase the level or effect of erythromycin base by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.nadolol, valsartan. Use Caution/Monitor. Avoid or Use Alternate Drug. Minor/Significance Unknown. Monitor Closely (1)potassium iodide and valsartan both increase serum potassium. This product is not intended to diagnose, treat, cure or prevent any disease. Contraindicated. Avoid or Use Alternate Drug. Coadministration may result in a significant decrease in renal function. Monitor Closely (1)valsartan increases toxicity of pitavastatin by Other (see comment). clonidine, verapamil. Monitor for symptoms of hypotension and edema when amlodipine is coadministered with CYP3A inhibitors to determine the need for dose adjustment. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.valsartan, meloxicam. Use Caution/Monitor. Avoid coadministration with sensitive CYP3A4 substrates with a narrow therapeutic index. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. NSAIDs decrease prostaglandin synthesis. verapamil increases levels of bosutinib by P-glycoprotein (MDR1) efflux transporter. The suggested Omega-3 dosage for people with blood pressure is 2000 to 3000 mg Omega-3 daily, combined with vigorous exercise, increased vegetable consumption and lower sugar. Use Caution/Monitor. Monitor Closely (2)verapamil will increase the level or effect of estrogens conjugated synthetic by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Depending on your specific brand, take this medication either in the morning or at bedtime as directed. Minor/Significance Unknown. Monitor Closely (1)calcium carbonate decreases effects of perindopril by unspecified interaction mechanism. Minor (1)verapamil increases levels of verteporfin by pharmacodynamic synergism. verapamil will increase the level or effect of solifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. valsartan, insulin inhaled. Discuss the risks and benefits with your doctor.This medication passes into breast milk, but is unlikely to harm a nursing infant. Additive hypotensive effects. Serious - Use Alternative (1)verapamil will increase the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Either increases toxicity of the other by Other (see comment). But tart cherry juice can be high in sugar so it's best to limit the amount you drink to about 4 oz to 6 oz, or no more than 8 oz per day in the context of an overall lower-sugar diet. Monitor digoxin levels closely when coadministered with drugs that may decrease glomerular filtration or tubular secretion. Use Caution/Monitor. Your email address will not be published. Modify Therapy/Monitor Closely. Coadministration of mild CYP3A4 inhibitors with midazolam intranasal may cause higher midazolam systemic exposure, which may prolong sedation. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Product labeling for PO topotecan recommends avoiding concomitant use of P-gp inhibitors; the interaction with IV topotecan may be less severe but is still likely of clinical significance. Use Caution/Monitor.Serious - Use Alternative (1)saquinavir will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Effect of interaction is not clear, use caution. Use Caution/Monitor. Consider decreasing the cilostazol dose to 50 mg twice a day. Monitor Closely (1)valsartan and potassium citrate both increase serum potassium. Monitor heart rate in patients taking ivabradine with other negative chronotropes. Use Caution/Monitor. Minor/Significance Unknown. Mechanism: pharmacodynamic antagonism. Serious - Use Alternative (2)verapamil will increase the level or effect of erythromycin lactobionate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Mitotane is a strong inducer of cytochrome P-4503A4; monitor when coadministered with CYP3A4 substrates for possible dosage adjustments. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.valsartan, diclofenac. Verapamil belongs to a class of drugs known as calcium channel blockers. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)glyburide will increase the level or effect of valsartan by Other (see comment). cornsilk increases effects of hydralazine by pharmacodynamic synergism. Mushrooms treated with UV lamps can produce even higher amounts of vitamin D. Use Caution/Monitor.verapamil will increase the level or effect of prednisone by P-glycoprotein (MDR1) efflux transporter. pharmacodynamic antagonism. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: severe dizziness, fainting, new or worsening symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain), very slow heartbeat.This drug may rarely cause serious (possibly fatal) liver disease. Use Caution/Monitor. Verapamil also inhibits P-gp activity, which can further increase apixaban serum levels; since both pathways of apixaban elimination are affected, patients with renal impairment receiving apixaban with drugs that are combined P-gp and moderate CYP3A4 inhibitors may increase exposure compared to patients with normal renal function; monitor for bleeding. Avoid or Use Alternate Drug. Monitor Closely (1)perindopril increases levels of potassium citrate by decreasing elimination. Exaggerated first dose hypotensive response. Avoid or Use Alternate Drug. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Risk of fetal compromise if given during pregnancy. verapamil will increase the level or effect of infigratinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)procainamide will increase the level or effect of verapamil by basic (cationic) drug competition for renal tubular clearance. Monitor Closely (1)valsartan and tolvaptan both increase serum potassium. Minor/Significance Unknown. Cholesterol-lowering effects of oat -glucan: a meta-analysis of randomized controlled trials. Monitor Closely (1)verapamil will increase the level or effect of fesoterodine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Sympathomimetics can antagonize the activity of some antihypertensive agents. The above information is provided for general Either increases toxicity of the other by Other (see comment). Everolimus prescribing information lists indication-specific dosing recommendations. Monitor Closely (1)perindopril, ethacrynic acid. Additive hypotensive effects. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. No dose adjustment is warranted at the 75 mcg dose. The researchers focused on studies that included at least 3 grams (g) of beta-glucan daily. Avoid or Use Alternate Drug. Use Caution/Monitor.verapamil will increase the level or effect of clozapine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Can increase risk of bradycardia. Either increases toxicity of the other by Other (see comment). This website also contains material copyrighted by 3rd parties. Monitor Closely (1)timolol and verapamil both increase anti-hypertensive channel blocking. verapamil will increase the level or effect of palbociclib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely.Serious - Use Alternative (1)verapamil, timolol. Use Caution/Monitor. Shop products from small business brands sold in Amazons store. Apalutamide weakly induces OATP1B1 and may decrease systemic exposure of drugs that are OATP1B1 substrates. Use Caution/Monitor. chlorpromazine increases effects of perindopril by unspecified interaction mechanism. Stonehenge Health strives to maximize each formula's effectiveness, perfecting each dose with the highest potency and purity of ingredients from trusted sources. Monitor Closely (1)perindopril, furosemide. calcium chloride decreases effects of verapamil by pharmacodynamic antagonism. valsartan and naproxen both increase serum potassium. Avoid or Use Alternate Drug. provider for the most current information. Use Caution/Monitor. There is concern that an overdose of ALA may cause a trace element deficiency in patients with diabetes mellitus. Use Caution/Monitor. Monitor Closely (1)conivaptan will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Other (see comment). Use Caution/Monitor. nifedipine will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Use Caution/Monitor. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: aliskiren, gold injections, lithium, sacubitril, certain drugs that weaken the immune system/increase the risk of infection (such as everolimus, sirolimus), drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone).Some products have ingredients that could raise your blood pressure or worsen your heart failure. Modify Therapy/Monitor Closely. aspirin/citric acid/sodium bicarbonate decreases effects of valsartan by pharmacodynamic antagonism. . Use Caution/Monitor.prednisone will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. 2020;12(4):1134. doi:10.3390/nu12041134. Use Caution/Monitor. Use Caution/Monitor. Most Neutralizes free radicals & oxidative damage. Modify Therapy/Monitor Closely. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Do not substitute tablets with capsules. verapamil will increase the level or effect of bazedoxifene/conjugated estrogens by affecting hepatic/intestinal enzyme CYP3A4 metabolism. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Both drugs decrease blood glucose. shepherd's purse, hydralazine. This effect was not observed with istradefylline 20 mg/day. Use Caution/Monitor. Use Caution/Monitor. Minor (1)shepherd's purse, valsartan. Use Caution/Monitor.dexamethasone will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Read More; I Have it Every Night! Monitor Closely (1)verapamil will increase the level or effect of repaglinide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil increases toxicity of lithium by pharmacodynamic synergism. sarecycline will increase the level or effect of verapamil by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor. Use Caution/Monitor. Risk of hypertension. 2 capsules taken daily preferably with meals or as directed by a healthcare professional. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. valsartan and trimethoprim both increase serum potassium. nefazodone will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Voxelotor increases systemic exposure of sensitive CYP3A4 substrates. methylphenidate will decrease the level or effect of valsartan by pharmacodynamic antagonism. Avoid or Use Alternate Drug. If coadministration unavoidable, separate administration by at least 6 hr before or after administration of P-gp substrates with narrow therapeutic index. verapamil will increase the level or effect of sufentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. ketorolac intranasal decreases effects of hydralazine by pharmacodynamic antagonism. Monitor Closely (2)ivacaftor increases levels of verapamil by P-glycoprotein (MDR1) efflux transporter. Suggested Use: As a dietary supplement, take two (2) veggie capsules once a day. Symptoms of overdose may include severe dizziness, weakness, fainting. Avoid or Use Alternate Drug. Monitor Closely (1)verapamil will increase the level or effect of cabazitaxel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)verapamil will increase the level or effect of estrogens esterified by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Minor/Significance Unknown. The mechanism of these interactions is likely related to the ability of NSAIDs to reduce the synthesis of vasodilating renal prostaglandins. Use Caution/Monitor. Some of the alpha lipoic acid that your body needs is derived from dietary sources. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. indinavir will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. perindopril increases effects of insulin detemir by pharmacodynamic synergism. ozanimod increases toxicity of verapamil by sympathetic (adrenergic) effects, including increased blood pressure and heart rate. Modify Therapy/Monitor Closely. pharmacodynamic antagonism. valsartan, quinapril. Additive hypotensive effects. Modify Therapy/Monitor Closely. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Avoid or Use Alternate Drug. Minor/Significance Unknown. Modify Therapy/Monitor Closely. Use Caution/Monitor.Serious - Use Alternative (1)verapamil will increase the level or effect of irinotecan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. If you have known medical condition or are taking any prescription medication, consult a physician before using this or any dietary supplement. Avoid or Use Alternate Drug. Keep taking this medication even if you feel well. Either increases effects of the other by pharmacodynamic synergism. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Use Caution/Monitor. Severe hypotension or syncope can occur. Contraindicated. pharmacodynamic antagonism. Because the active metabolite of ozanimod inhibits MAO-B in vitro, there is a potential for serious adverse reactions, including hypertensive crisis. Use Caution/Monitor.verapamil will increase the level or effect of tacrolimus by P-glycoprotein (MDR1) efflux transporter. Daridorexant dose should not exceed 25 mg per night when coadministered with moderate CYP3A4 inhibitors. Serious - Use Alternative (1)rifampin will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. hydralazine will increase the level or effect of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Mechanism: pharmacodynamic synergism. Other (see comment). verapamil will increase the level or effect of oxybutynin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. WebContraindications. Effect of interaction is not clear, use caution. Combo may increase risk of hypotension, bradycardia, AV block. Either increases effects of the other by pharmacodynamic synergism. secobarbital will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)trimethoprim and perindopril both increase serum potassium. Monitor Closely (1)hydralazine, phenelzine. Monitor Closely (1)verapamil will increase the level or effect of lefamulin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. At this time there is not an agreed upon daily requirement of beta glucans. Minor/Significance Unknown. Use Caution/Monitor. Modify Therapy/Monitor Closely. Sinus bradycardia resulting in hospitalization and pacemaker insertion has been reported in association with the use of clonidine concurrently with verapamil. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (1)verapamil will decrease the level or effect of clopidogrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. verapamil will increase the level or effect of repaglinide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil increases levels of ibrutinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Either increases toxicity of the other by Other (see comment). Mechanism: pharmacodynamic synergism. Use Caution/Monitor. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect. Risk of hyperkalemia. This medication is also used to prevent heart attacks in people with a certain type of heart disease (stable coronary artery disease). Modify Therapy/Monitor Closely. valsartan, perindopril. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Use Caution/Monitor. Minor/Significance Unknown. Use Caution/Monitor. Use Caution/Monitor.verapamil will increase the level or effect of diltiazem by affecting hepatic/intestinal enzyme CYP3A4 metabolism. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. If concurrent short term (14 days or less) use of moderate CYP3A inhibitors is unavoidable for patients who are taking cobimetinib 60 mg, reduce the cobimetinib dose to 20 mg. After discontinuation of a moderate CYP3A inhibitor, resume cobimetinib 60 mg. Use an alternative to a moderate CYP3A inhibitor in patients who are taking a reduced dose of cobimetinib (40 or 20 mg daily). Use Caution/Monitor. Direct vasodilator; dilates arterioles with little effect on vein; decreases systemic resistance, which subsequently decreases blood pressure. meloxicam decreases effects of valsartan by pharmacodynamic antagonism. Monitor Closely (1)piroxicam decreases effects of hydralazine by pharmacodynamic antagonism. affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Monitor Closely (1)valsartan increases and metolazone decreases serum potassium. nitroglycerin rectal, verapamil. Monitor plasma levels when used concomitantlySerious - Use Alternative (1)carbamazepine will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. verapamil will increase the level or effect of clomipramine by affecting hepatic enzyme CYP1A2 metabolism. amiodarone, verapamil. fenoldopam, hydralazine. Risk of hypertension. Minor/Significance Unknown. Avoid or Use Alternate Drug. prescription products. NSAIDs decrease synthesis of vasodilating renal prostaglandins, and thus affect fluid homeostasis and may diminish antihypertensive effect.perindopril, sulfasalazine. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Use Caution/Monitor. verapamil will increase the level or effect of methylprednisolone by P-glycoprotein (MDR1) efflux transporter. Avoid or Use Alternate Drug. This product is from a small business brand. Use Caution/Monitor. acemetacin decreases effects of perindopril by pharmacodynamic antagonism. Avoid or Use Alternate Drug. Monitor Closely (1)valsartan increases effects of exenatide injectable solution by Other (see comment). Coadministration may result in a significant decrease in renal function. Avoid or Use Alternate Drug. Use Caution/Monitor. methyclothiazide will increase the level or effect of verapamil by basic (cationic) drug competition for renal tubular clearance. Monitor Closely (1)verapamil will increase the level or effect of mexiletine by affecting hepatic enzyme CYP1A2 metabolism. Monitor Closely (1)armodafinil will decrease the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. valsartan increases and ethacrynic acid decreases serum potassium. Minor/Significance Unknown. Use Caution/Monitor. pharmacodynamic antagonism. Use Caution/Monitor. Monitor Closely (1)perindopril, eplerenone. Minor/Significance Unknown. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. Minor/Significance Unknown. Avoid or Use Alternate Drug. Monitor Closely (1)verapamil will increase the level or effect of streptomycin by P-glycoprotein (MDR1) efflux transporter. verapamil will increase the level or effect of antipyrine by affecting hepatic enzyme CYP1A2 metabolism. Avoid or Use Alternate Drug. Monitor Closely (1)verapamil will increase the level or effect of alfentanil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Monitor Closely (1)sarecycline will increase the level or effect of verapamil by P-glycoprotein (MDR1) efflux transporter. Monitor Closely (1)tenofovir DF increases levels of verapamil by decreasing renal clearance. Do not store in the bathroom. IDM Members' meetings for 2022 will be held from 12h45 to 14h30.A zoom link or venue to be sent out before the time.. Wednesday 16 February; Wednesday 11 May; Wednesday 10 August; Wednesday 09 November Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Avoid or Use Alternate Drug.verapamil, temsirolimus. Use Caution/Monitor. Use Caution/Monitor.iloperidone increases levels of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Dual blockade of renin-angiotensin system increases risks of hypotension, hyperkalemia, and renal impairment. Monitor Closely (3)verapamil will increase the level or effect of cortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. perindopril, furosemide. commonly, these are "non-preferred" brand drugs. Avoid or Use Alternate Drug. Use Caution/Monitor. Use Caution/Monitor. Minor (1)tizanidine increases effects of perindopril by pharmacodynamic synergism. Avoid coadministration with other drugs that decrease pulse or blood pressure to mitigate risk of excessive bradycardia and hypotension. Avoid or Use Alternate Drug. Contraindicated. Use Caution/Monitor. Monitor Closely (1)tadalafil increases effects of valsartan by pharmacodynamic synergism. If coadministration is unavoidable, reduce tazemetostat current dose (see drug monograph Dosage Modifications). Monitor glycemic control especially during the first month of treatment with an ACE inhibitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (2)istradefylline will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. valsartan and ketorolac both increase serum potassium. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. letermovir increases levels of valsartan by Other (see comment). Use Caution/Monitor. Avoid or Use Alternate Drug. Monitor Closely (1)sevelamer decreases levels of verapamil by increasing elimination. WebWe took 250mg of organic Lions Mane (per serving), a functional, nootropic mushroom, which has been used around the world for centuries for increased focus and creativity, and combined it with our delectable, organic fair trade coffee. Use Caution/Monitor.Minor (2)verapamil will increase the level or effect of clomipramine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil increases toxicity of doxorubicin liposomal by decreasing metabolism. Stonehenge Health strives to maximize each formula's effectiveness, perfecting each dose with the highest potency and purity of ingredients. perindopril increases effects of glyburide by pharmacodynamic synergism. Other (see comment). The results from an in vitro study with human liver tissue indicate that valsartan is a substrate of the hepatic uptake transporter OATP1B1; coadministration with OATP1B1 inhibitors may increase valsartan systemic exposure ritonavir will increase the level or effect of valsartan by Mechanism: decreasing hepatic clearance. Either increases effects of the other by pharmacodynamic synergism. Monitor Closely (3)valsartan, ibuprofen. Use Caution/Monitor. Mechanism: pharmacodynamic synergism. Use Caution/Monitor. Sympathomimetics can antagonize the activity of some antihypertensive agents. Use Caution/Monitor. Monitor Closely (1)verapamil, bretylium. Risk of fetal compromise if given during pregnancy. Both drugs decrease blood glucose. Use Caution/Monitor. Use Caution/Monitor.fenoprofen decreases effects of valsartan by pharmacodynamic antagonism. telmisartan, perindopril. The recipient will receive more details and instructions to access this offer. Can eating mushrooms help lower cholesterol? perindopril, oxaprozin. Methylphenidate may diminish antihypertensive effects. Monitor Closely (1)levodopa increases effects of hydralazine by pharmacodynamic synergism. Closely monitor for arrhythmias and events (eg, syncope, heart palpitations) since lonafarnib effect on QT interval is unknown. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. verapamil increases effects of atracurium by pharmacodynamic synergism. valsartan and nebivolol both increase serum potassium. Minor (1)maitake increases effects of verapamil by pharmacodynamic synergism. Minor (1)valsartan, entecavir. Use Caution/Monitor. verapamil will increase the level or effect of irinotecan liposomal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. WebOur Commitment to Anti-Discrimination. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. Use Caution/Monitor. Minor (1)tizanidine increases effects of hydralazine by pharmacodynamic synergism. Most Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. maitake increases effects of valsartan by pharmacodynamic synergism. Use Caution/Monitor.silodosin and verapamil both increase anti-hypertensive channel blocking. Use Caution/Monitor. Minor/Significance Unknown. valsartan and ketoprofen both increase serum potassium. Use Caution/Monitor. Closely monitor for increased adverse reactions and modify dose of darolutamide as needed when coadministered with drugs that are both P-gp and strong or moderate CYP3A4 inhibitors. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. 2017;18(9):1906. doi:10.3390/ijms18091906. Modify Therapy/Monitor Closely. pharmacodynamic antagonism. Monitor Closely (1)caspofungin will increase the level or effect of valsartan by Other (see comment). valsartan and sotalol both increase serum potassium. Avoid or Use Alternate Drug. Either increases toxicity of the other by Other (see comment). Avoid or Use Alternate Drug. Minor/Significance Unknown. Either increases toxicity of the other by unspecified interaction mechanism. If coadministration of CYP3A4 inhibitors with fentanyl is necessary, monitor patients for respiratory depression and sedation at frequent intervals and consider fentanyl dose adjustments until stable drug effects are achieved. Decrease eluxadoline dose to 75 mg PO BID if coadministered with OATP1B1 inhibitors. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor.Minor (1)verapamil increases levels of desipramine by decreasing metabolism. May inhibit organic anion transporter polypeptides; decrease dose of angiotensin receptor blockers and monitor patients for signs and symptoms of hypotension and/or worsening renal function; if such events occur, consider further dose reduction of angiotensin receptor blocker or switching to alternative to angiotensin receptor blocker Minor (1)ombitasvir/paritaprevir/ritonavir & dasabuvir (DSC) will increase the level or effect of valsartan by decreasing elimination. After viewing product detail pages, look here to find an easy way to navigate back to pages you are interested in. perindopril, spironolactone. Use Caution/Monitor. Monitor Closely (1)hydralazine, phenylephrine. Use Caution/Monitor. Use Caution/Monitor.meloxicam decreases effects of valsartan by pharmacodynamic antagonism. Monitor Closely (1)valsartan and potassium chloride both increase serum potassium. Minor (1)verapamil will increase the level or effect of estradiol vaginal by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.verapamil will increase the level or effect of indinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Use Caution/Monitor. valsartan, moexipril. Use Caution/Monitor. Use Caution/Monitor. Stimulates microbiome growth for fully functional digestive system and immune system support. Use Caution/Monitor. Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Modify Therapy/Monitor Closely. elagolix decreases levels of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. verapamil will increase the level or effect of fexofenadine by P-glycoprotein (MDR1) efflux transporter. Heart Failure (Off-label) affecting hepatic/intestinal enzyme CYP3A4 metabolism. valsartan and oxaprozin both increase serum potassium. affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Monitor Closely (1)valsartan increases toxicity of fluvastatin by Other (see comment). Increased risk of neurotoxicity. Use Caution/Monitor. Minor/Significance Unknown. Minor/Significance Unknown. Monitor heart rate in patients receiving concomitant verapamil and clonidine.verapamil, clonidine. DRUG INTERACTIONS: See also Precautions section.Drug interactions may change how your medications work or increase your risk for serious side effects. Dietary sources pulse or blood pressure to mitigate risk of excessive bradycardia hypotension. Unavoidable, reduce the synthesis of vasodilating renal prostaglandins two ( 2 ) will... Lowering agents may increase serum potassium least 50 % at least 6 hr before after! To 50 mg twice a day discuss the use of clonidine concurrently with verapamil up to 12 for... How recent a review is and if the reviewer bought the item on.... By decreasing metabolism Wort will decrease the level or effect of fesoterodine by affecting hepatic/intestinal enzyme metabolism... 3 ) verapamil will increase the level or effect of verapamil by affecting hepatic/intestinal enzyme CYP3A4 metabolism if coadministered OATP1B1. Triazolam by affecting hepatic enzyme CYP1A2 metabolism provided for general either increases toxicity of the other by mechanism: synergism! To view formulary information first create a list of plans for renal clearance. Insulin glargine by unspecified interaction mechanism bradycardia, AV block reduce renal function or compete active. Associated with amifostine medications work or increase your risk for serious side effects for adjustment...: this is a summary and does not have all possible information about this product that body... 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The coadministered drug is also used to prevent heart attacks in people with a certain type of heart (.